I have not been asked about the long-term colonizing of Mars yet so I thought I’d make it clear that I’m not in favor of it. Just imagine living in a super-isolated pressure can 24/7 on a very cold world with no breathable air. It would be like going to jail with the added risk of asphyxiating and freezing to death all at once. No flora or fauna to cheer things up. Just the same tiresome people with the same tiresome board games to play. No smells beyond that of other people. Over time cliques and romance may form and dissolve into antagonism. No web of life other than just you and your gut flora.
You: Wanna go to Mars?
Me: What, are you nuts??
Lamentations on Chemistry 
Will it be a Second Amendment zone?
Just wondering.
I’m sure that citizens will arrive fully armed with nerf darts rather than guns. They won’t want to shoot holes thru the walls of the metal cans they are living in. There will be no nearby Home Depot or Lowe’s to go and buy duct tape.