Category Archives: Uncategorized

Things I’d like to see

Here are three items on my wish list for the future. There are more but this is enough for today.

  • The nomination of Donald Trump as Republican candidate for president in 2016. This political intestinal disease needs to run its course. Hell, let him win in 2016. Why? Given that a win means the electoral system has spoken, the GOP will have to reconcile this unforeseen event to the rest of the electorate and to the Citizen’s United beneficiaries who were accordingly disappointed. Perhaps there will be leadership purges at both the RNC and DNC. Even more fantastical would be a rethinking of what the parties stand for. But … nah. It won’t happen.
  • Fewer movies about Nazis. It is a tired and tiresome meme. Move on.
  • I’d like to see the Rupert Murdoch empire taken to task over their FCC broadcast licenses. Recalling that the public airwaves are just that, I’d like to hear them explain how his use of broadcast spectrum really merits the public trust. The same goes for other news outlets and cable providers. But before Murdoch croaks, I’d like to see him squirm.

<< cue theme song>>

 

Company gets public spanking from CSB

The US Chemical Safety Board (CSB) has publically expressed dismay and disappointment in a letter to Tesoro Corporation in San Antonio, TX. It is in regard the apparent unwillingness of the company to allow CSB investigators to come on site and continue with the investigation of an industrial accident or, if you prefer, incident. Apparently two workers were splashed with sulfuric acid and had to be choppered out for treatment.

From what I gather from the CSB letter, Tesoro doesn’t believe that the incident rises to the level of seriousness to justify a CSB investigation. That is my own interpretation.

At first blush it would seem that Tesoro has a point. While it is something that OSHA would cover, does it really necessitate attention by the CSB? By itself it seems questionable. But when you consider that Tesoro had an 7-fatality explosion and fire at its Anacortes refinery in April of 2010, perhaps the scrutiny seems less unreasonable.

The refinery explosion was determined to result from high temperature hydrogen attack within a 40 year old shell and tube heat exchanger. Catastrophic structural failure on startup after a scheduled tube cleaning resulted in an explosion and fire with immediate and delayed fatalities.

It seems to me that the failure of a high temperature heat exchanger after 40 years of service handling hydrogen and naphtha has more to do management policy on equipment service life than anything else. This speaks to prudent administrative and engineering controls on plant safety. A shell and tube heat exchanger has no moving parts to fail. It just sits motionless doing it’s function. There are no failing parts to replace other than leaky tubes and valves. Perhaps no one considered that the inherent nature of the gas and thermal cycling was deleterious to the integrity of the metal shell? Perhaps there was no enthusiasm to define official hours of operating life. Plant managers are always under pressure to minimize operating costs. This is especially true of plants producing high volume low margin commodities.

But here is the rub. Everything has a failure rate. This is especially critical for equipment under high temperature and pressure. The first layer of administrative control is for management to make allowances for materials in extreme environments. Anacortes is not the only recent incident where component failure has occurred in equipment performing under demanding conditions. Before the engineers can make equipment specifications for this, management has to conform to the notion that some parts of a plant should have better definition on service life. They should demand it of their design people and support engineering when the time comes to replace a component.

If the CSB believes that a company has weak administrative controls that influence plant safety, then I think they should investigate.

Attacking Syria for nerve gas use in Ghouta

In the news there are reports of pending action by the US in Syria. Maybe I have a blind spot. Maybe there is some fundamental principle I am missing here. But how is it that a mass killing by gas elicits a response from the US when a larger mass killing by bullets and high explosives does not? Where are sympathetic Arabs in the region? How are they exempt from delivering bombardment as justice for the dead?

Obviously, gas attacks lie across a firebreak of some kind. What is the Syrian death toll now- 90,000 + by bullets and bombs? And that does not trigger international action? Apparently, grisliness is not a deciding factor.

This isn’t about justice at all. It is a smack down on setting a precedent with NBC warfare- nuclear, biological, and chemical. It is a genie we cannot allow out of the bottle … in the land of the genie.

So, here is the scenario-  the US will begin a strike at 3 am with cruise missiles to soften up the target area and air defenses. Stealth fighters will fly in to attack everything that flies. Penetrator missiles will demolish air, missile, and command and control bases. But what to do about the nerve gas armaments? Are they bombed or isolated? Who recovers them right after the attack? Al Qaeda? Let’s hope not.

This whole thing is a troubling moral discontinuity. By policy we watch many tens of thousands murdered by bullets and high explosives, but act on policy that triggers when gas is used. There may not be an answer, but there certainly is a smell. The smell of death.

The Squamous Chronicles. Finish one and start another.

8/27/13.  As of today, I have 3 more x-ray treatments culminating in a dose of 63 Gray to the throat. The pain has required narcotics pretty much continuously and the attendant constipative delights that go with that. Pills are difficult to swallow and the gag reflex is heightened. The final chemo was yesterday so I am done eating platinum.

I began hormone ablation treatment for an aggressive form of prostate cancer two weeks ago. While the throat cancer is substantially beatable, the prostate is a different story. Here is the deal fellas. While you can gauge with PSA numbers, it is the Gleason grading system that tells the tale. And to get that you must do a biopsy. In order of increasing severity, the Gleason score goes from 2 to 10. I pulled a 9.

Hormone ablation is delicate way of saying chemical castration. The spread of prostate cancer can be controlled somewhat for up to 2 years by shutting down testosterone production. This they do by injecting a synthetic peptide, Degarelix, into belly fat to control the dosing to the pituitary gland. Had my first hot flash a week ago. It was a eunuch sensation.

Interesting anecdote.  My medical oncologist described an MD patient who had been using sunscreen on the radiated area of his throat. He soon experienced an increase in surface burning of the throat on continued x-radiation. Turns out he was using a sunscreen that had titanium dioxide that was scattering/absorbing radiation on the affected surface. He stopped and the accelerated damage ceased.

The Squamous Chronicles. Radiation, biopsy, gastric tube and chemo.

As of today, I am 18/30 of the way through radiation. Last week I was unable to eat much, resulting in a large weight loss (ca 10 wt %) and necessitating the placement of a gastric tube. This was done under general anesthesia, but while I was awake. A fluoroscope was used to view the procedure. This was a bizarre experience. I could feel the stomach being punctured and sutured to the abdominal wall.

As weird as this experience was, it was nothing compared to the prostate biopsy the next day. Eight corings of the prostate though the rectum wall producing 8 little meat sticks of sample. It felt like the snapping of a tight rubber band against the tissue. The doc tried to ask about my hobbies during the procedure for distraction. Glad that is over.

The biggest side effect of this has been fatigue. I’ve experimented with more exercise to good effect. Freshly juiced vegetables help compensate for the drug induced constipation. And a large influx of calories through the gastric tube all add up to an improved energy level. I have been juicing beets and swiss chard.

In general, owing to the radiation on the throat (they say) my taste buds are operating improperly. Everything tastes really bad.

This week, a day past the third 90 mg drip of cisplatin, I am experiencing hair loss.

CERN to make announcement Wednesday, July 4, 1012

According to the CERN website, a webcast on LHC experiments is planned for, Wednesday, July 4, 2012. Apparently a new particle has been detected. Could it be the big chalupa? The Higgs boson?

CERN has previously announced resonance data at the expected energy but cautioned that the correlation by the requisite number of sigma’s was not in hand. In the US, a similar announcement was issued the other day from Tevatron data in Illinois. Same problem- not enough sigma’s. Hmmm. I wonder what CERN is going to say tomorrow wink wink nod nod?

On a side note, according to Quantum Diaries, researchers at CERN run Monte Carlo collision simulations for comparison purposes to the actual data stream. If events occur that are not anticipated by the simulations, then there is cause to examine the particular events. Interesting approach to sorting the data.

Denver ACS Meeting

Just back from Day 1 at the Denver ACS meeting.  Spent the afternoon at the INORG session celebrating the 50th anniversary of the journal Inorganic Chemistry.  As usual, Harry Gray stole the show with his talk- today it was on oxo complexes. What I like about Gray is that he shows the younger members that being socially constipated is not manditory for success in chemistry.  Maybe it’s his delivery, but after a Gray talk I leave feeling like I have gotten a glimpse of the future.

Attendance is down a bit due to hurricane Irene.  Looks like the Atlantic coast dodged the bullet. Earth quakes, hurricanes … what next? Cane toads?

Afganistan: US Fights While China Mines Copper

From an article by reporter Alex Rodriquez in the Tuesday, July 12, 2007, LA Times entitled “History succumbing to the allure of ore”.  The article describes efforts by archeologists to dig sites in an area southeast of Kabul soon to be razed by bulldozers in preparation for copper mining.

So, I understand the part about saving the archeology.

What I fail to understand is why the US is fighting in Afganistan, expending national treasure consisting of the lives of soldiers, equipment, and mountains of cash, while the China Metallurgical Group is busily extracting copper.

USA fights for “freedom”, expending vast treasure.  China’s communism overrides freedom yet digs and extracts treasure.  Really now.

Are we congenital fools?  Are the Chinese at least thanking us for making Afganistan safer for them?  The wars in Afganistan, Iraq, and Pakistan are estimated to cost the US 3.7 trillion dollars.  These wars have produced wealth for defense contractors and for China through it’s mining.  At home republicans are busy sheltering corporations and the wealthy from tax liability while trying to apply wingnut libertarian economic theory to justify why we can’t commit resources at home. 

Most republicans are not wealthy. Yet, republican ranks are jam packed with people of modest means who support a doctrine and a silent power base of wealth who will not reciprocate the support.  It’s utterly irrational.

This is too crazy for words.

Whither Diethyl Ether?

Diethyl ether seems to be in short supply in North America these days. Suppliers have customers under allocation constraints.  Yes Virginia, people still use Et2O in certain kinds of chemical processing. Sometimes Et2O is prized for its solvent effects and sometimes for its volatility. Sometimes the only way to solubilize some  inorganic compounds is as the metal etherate.  Solvent residues in fine chemicals are often a problem and volatile process solvents can be a big help in ameliorating that issue.  You can purchase 5,000 gallon tanker loads of Et2O if the supplier has qualified you. Another reason not to swerve in front of trucks on the highway. 

Part of the problem with Et2O availability is the considerable reduced demand for it these days.  Many companies have banned the use of Et2O on their site for any purpose. It is easy to understand why. The insane vapor pressure and low autodecomposition temperature are problematic for plant safety. The low boiling point of Et2O means that plant utilities can heat a vessel of ethereal soln rapidly and blow a rupture disk at reasonably low pot temps.  Naturally, the safetly department gets surly about this kind of thing.

Tetrahydrofuran is not always a suitable process stand-in for Et2O. Reactivity behaviors may be quite different from Et2O solns.  THF’s sensitivity to butyllithium, for instance, forces one to keep the processing conditions at low temp with a chiller. Lower pot temperatures increase the thermal margin of safety, but may have a deleterious effect on activation of a transformation once BuLi has done its job. 

I have studied the decomposition of methyl tetrahydrofuran with BuLi and have determined that it decomposes in the low 30’s °C range, somewhat higher than THF. MeTHF is not an exact stand-in for THF or Et2O either.  But it is definitely worth having in the stockroom for development work. It will surprise you in regard to how different it can be from THF.

While MeTHF is touted for its ability to phase separate with water, it will hold appreciable amounts of water.

Out of the ditch and on the road

I have decided to continue scribbling in this blog. Th’ Gaussling has cut loose some psychic energy sinks that have been bogging me down.  There are too many problematic characters in my work life to welcome them gladly into a volunteer life as well. Many of us (i.e., large, irritable animals) aren’t cut out to be happy and compliant volunteers.

Writing is something I need to do on a regular basis. Writing in a private diary isn’t nearly exciting enough. I enjoy the trickle of commentary and the colorful characters out there in the blogosphere.