A Week in Krung Thep

I startled to wakefulness by the sharp crack of nearby lightning. I had resolved to synch into the local time by remaining awake until evening, but failed shamefully. I stumbled to my feet and walked to the rain spattered window of my 21st floor room.  From this vantage I could study the cityscape of Krung Thep (Bangkok) and marvel at the activity on the muddy Chao Phraya river below. 

BKK

The television blares out that reassuring theme music of the BBC- the one with the swirling red pattern against the beeping time signal in the background. Despite all of my travel, it still boggles my mind how comfortable it is to go to distant places. You sit in an aluminum tube for a while, get out, and hop into a taxi.

The conference is in a 5-star luxury hotel, filled to the brim, it seems, with nattering western 60-somethings on holiday. Prosperous Europeans and North Americans out for a taste of exotic Siam. Nothing too strong mind you, just a taste.  The air-conditioned, hospital-clean hotel offers the one thing that you can’t get otherwise in Krung Thep- solitude.

A step into the streets of the city is, for this North American, a step into the heart of metropolitan Asia. It is monsoon season, so the air envelops you like a hot, wet sweater smelling of diesel and oily 2-stroke motor exhaust. Everyone is busy. Some are just moving from point A to B. Others are eyeing you from their narrow kiosks and calling out for your business.  Like the stationary bivalve that eats only when it can suck in some bystander, the kiosk proprietor has but 15 seconds to get catch your fancy before you leave the field of view. As a westerner, you resemble a big block of cheese and everyone wants a slice.

All of the motion, the incessant bartering and angling for prices is always a shock to Americans who are used to the economic firmament of price tags and the taboo of public bickering over prices.  Americans pride themselves on capitalism, but are reluctant to let it equilibrate to the microscopic level of one-on-one haggling with shopkeepers. Too untidy and confrontational. Americans would rather go to another store than attempt to haggle for a better price.  But this reluctance only serves to dilute the power of the consumer. This is a lesson we can take from Asia.

Far Side of the World

In chemistry, nothing is easy. Everything has failure modes. It’s possible to screw up when putting water in drums. My ham-fisted attempts at a new reaction pathway for a thorny, expensive process have thus far lead to naught. Nature has hidden some subtle requirements that are yet unknown to me. Application of known processes to new substrates may suffer failures that seem obvious afterwards, but are opaque going in.

I used to joke that if one in ten reactions lead to a good result I was doing well.  It’s not always that bad, but you can have stretches where the most reasonable transformations fail in one way or other. Unfortunate side products, poor yields, wrong selectivity, yada, yada, yada. Try doing the last experiment first, they say.

Th’ Gaussling is off to the far side of the world next week for a conference. A week in Bangkok will offer some needed punctuated disequilibrium.  The down side- 20 hours of confinement in an aluminum tube with wheezing strangers. I would prefer to be sedated and put in a box for transport than sit in an airline seat for that long.

Unplanned Comedy

So, I was standing on a ladder in the basement late this afternoon, draining the water line to the sprinkler system from a valve high inside the basement wall. The lawn care guy was outside with a high pressure air line connected to the sprinkle system waiting for my signal to blow down the line.

Suddenly there was a surge of high pressure water spraying into my face and down the wall of the basement. I started screaming “Stop! Stop the water!!”. Fumbling for the valve in the deluge of water I realized that the flow would only stop if I could screw the small brass cap back onto the valve. As I fumbled in the spray, the water flow tapered off giving way to air and finally stopped.

Drenched, I walked outside to find that the fellow felt bad, but was also laughing pretty hard. I started laughing too and we agreed that it was kinda funny. We got the job finished and went about our business.

October 10 Nobel Prize Announcement

Note added 10/10/07– Gerhard Ertl won the prize for his work relating to surface science.  Looks like there is no future for me in the prediction game. That’s why I’m not Th’ Oracle.

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Any guesses as to who is going to win the Nobel Prize for Chemistry? I’m guessing Whitesides will be one of them. But, opinions are like noses- everyone has one. What do you think?

I mean, after all, he’s won everything else. Well, except for a slot on American Idol.

Publishing in Open Access Journals

In the course of searching chemical topics I keep running into the on-line publication Molecules, A Journal of Synthetic Organic Chemistry and Natural Product Chemistry.  This journal is part of MDPI, Molecular Diversity Preservation International, with an office in Basel, Switzerland.  MDPI is also dedicated to the “deposit and exchange of molecular and biomolecular samples”.

The idea behind this journal is to provide open access. The journal asserts that, with this approach, articles get substantially higher citation numbers. Open access is an alternative to paid subscriptions. In this model, the author pays the publication fee up front for peer reviewed editorial oversight and rapid publication.

This was covered by C&EN in the July 3 of 06 issue. It was stated in the article that Elsevier was planning to offer the same service for authors who wanted free access for a cool US$6,000 per article.  The Public Library of Science has a similar program, but with a more reasonable price structure.

What I find especially exciting about this publication mode is the MolBank service. Have you ever ended up with new compounds or data that was perhaps deserving of disclosure but not part of a body of work that would develop into paper?  Here is a blurb from the website-

Molbank (ISSN 1422-8599, CODEN: MOLBAI) publishes one-compound-per-paper short notes and communications on synthetic compounds and natural products. Solicited timely review articles will also be published. Molbank was published during 1997-2001 as MolBank section of Molecules (ISSN 1420-3049, CODEN: MOLEFW). Since 2002 it is published as a separate and independent journal. Molbank is a free online Open Access Journal. To be added to the subscriber’s mailing list, write your e-mail address into the “Publication Alert” box on the right side, and press the “Subscribe” button. Molbank is indexed and abstracted very rapidly by Chemical Abstracts.

Interestingly, this could be a possible venue for defensive disclosures in intellectual property. Hmmm … 

The question is, will paying-to-publish be cheaper than paying-to-subscribe? And, how will library administration have to change to accommodate this? 

But perhaps the bigger issue may be related to a certain snobismus that exists in regard to publishing. At some point, the rock stars of research (Whitesides, Trost, etc.) need to wave their hands over this mode of publishing and utter something like “verily, it is good” so the rest of the herd will thunder in that direction.

The writer of this blog has vented on this issue several times.  Putting public financed research results into free public access is the fair thing to do and should contribute to innovation and get new technologies into use at lower cost.  Turning over copyright of research papers to private third party groups only adds to the expense and complication to the use of this national treasure.

No doubt this will be vigorously opposed by the publishing establishment. The US$6000 fee charged by Elsevier is absurd and in reality is the beginning of the end of their publically financed milking of the R&D cash cow.

Halliburton and the Bush II Krewe

Anymore, criticizing the Bush administration is like having an unproductive cough- the stuff is so deep in there that you can’t hack up the obstructing mass. And so it is with the current president and appointees, who are insinuated into the deep recesses of power like a resistant strain of waxy mycobacterium. 

Serial government haters all, the Bush II krewe has privatized large chunks of gov’t service work and handed it on a no-bid platter to loyal backers like Halliburton who are largely registered in tax haven countries.

Unwilling to make the ultimate commitment to the USA (or wanting cover its tracks), Halliburton moved its headquarters to the United Arab Emirates. Presumably to take advantage of the tax-free business environment and the lack of a troublesome extradition treaty with the USA.  The status of Halliburton as a foreign contractor needs to be examined in public. 

Yes, this is old news, but Americans should not forget this outrage.  According to HalliburtonWatch, Cheney himself increased the number of foreign tax haven subsidiaries from 9 to 44 during his time there as CEO. 

There is nothing illegal about taking advantage of tax law.  But at some point a company has to decide what country they support and what side of history they want to be on. That which is possible is not necessarily manditory. When money is the only scorecard, ethics fly out the window. Stockholders bear as much responsibility for this craven behaviour as do the officers. [*crunching* noise as I step off the soapbox]

Halliburton became a successful company in part through it’s use of resources provided by the US taxpayer.  Halliburton used US government funded highways to get its goods and services moved around the US. Their security was provided by the Army, Navy, Air Force, and the Marines.  Halliburton staff and stockholders are protected from epidemic by the Centers for Disease Control. Sewage from Halliburton office buildings goes into local municipal  waste treatment plants. Physicians trained in publically subsidized medical institutions lance their boils and treat their childrens ear infections. The list of benefits from public infrastructure is substantial.

Now these greedy corporate ex-patriots want to shelter their earnings from tax liability. They don’t want to contribute to the upkeep of the very system that facilitated their ascent to wealth.

This entire thing is so dirty and so extensive, it will take a generation to understand it and legislate corrective action. The whole fetid, reeking mess is offensive.

Dawkins: Speaking the Ineffable

Warning!! The following text contains links and declarative statements that may cause chafing or philosophical infarct.

The Richard Dawkins BBC programs “The Root of All Evil, Part 1 and Part 2“, are quite worth the time to view. It will no doubt be uncomfortable for some. Dawkins is very much a promoter of reason and doesn’t restrain his blunt questions at all. 

What is interesting to witness is Dawkins’ genuine surprise when a few characters respond with an absolute and even threatening rebuff to his reasoning.  I think he truly expected to move these people to see his point of view by the force of reason.  In many ways, this program portrays a world very hostile to the analysis of belief.

The whole notion of belief as an inviolable, sacrosanct capsule of “vital essence” seems to be hardwired into our brains.  For many, the prospect of another person drilling into your personal theory of the universe (God or physics) is both profane and invasive.  Like most people, I am not keen on being “examined” like some analytical sample either. But in the end, a “theory of everything” that can’t survive scrutiny is not worth having.

Perhaps where Dawkins goes astray is at grasping the difference between being analytically correct and just being comfortable with an idea.  Few people have the overlap of both curiosity and the opportunity to cover some new ground in the scholarly examination of the Big Questions.  In fact, it seems that the methodical pursuit of novelty is not a universal trait in culture.  A great many people are perfectly happy to live and believe as the ancestors did. 

Dawkins is not shy about drilling into the bedrock of belief. I think between Dawkins, Harris, and Dennett, there is a growing realization that religion should be studied analytically as a natural phenomenon rather than exclusively as a subject of devotion. 

Communication Codewords

Within organizations there are always people who are very quick to demand better communication. When you hear them make this statement, you might understandably believe that they wanted more information out on the table for discussion. One could take this to mean that their intent was to come to a group concensus.  And, for some people this is the case.

But for others, the word “communication” is a kind of code word. It means something like this- “YOU need to disclose this information so I can make the call on what is going to happen”. It is about control, and in most organizations much of the day to day conflict that arises has to do with control over some kind of resource. It is the root cause of much bad behaviour by grownup persons who should know better. When you think about it, power is about the the ability to allocate resources.

Many people who bark about communication are vocal about receiving it, but are poor at reciprocating.  That is, they are an information black hole, or a kind of WOM-  Write Only Memory. Such folks are great at demanding information, but somehow can’t be as diligent about it themselves.

If you have a leadership role where these kind of conflicts are occuring, the best thing to do is to bring conflicting parties together and mediate or facilitate the communication between them.  If you are not in a leadershop role, the best thing to do is to be guilty of generosity with information.  Send information by email and save copies of the correspondence for CYA.

Enomagnetic Resonance

Nuclear Magnetic Resonance spectroscopists have finally crawled down off their crosses and condescended to the application of their technology to something really useful- the study of wine NMR spectra. If you believe the attached article, a restaurant in NJ has purchased an NMR spectrometer for the purpose of determining the quality of wine.  Evidently, the contents of a cork-sealed bottle can be examined by proton and 13C NMR.

Jeepers.  I wonder if it is hard to get boxed wines to spin inside the magnet? \;-)

One question. Does the rotating frame turn the opposite direction for Australian wines? 

Chemical Business in Russia- One Experience

Hearing of the passing of Boris Yeltsin, I can’t help but remember my trip to his northern empire in 2000.  We boarded a Lufthansa flight in Frankfurt, seemingly filled to the scuppers with jabbering Russian tourists anxious to return from their trip abroad. We left rainy Germany for the port city of St. Petersburg, near the mouth of the Neva River. Most of the terrain was obscured beneath heavy clouds so there was nothing to see until our descent at 10:30 pm. The sun sets late at 60 degrees north in the spring.  As we were coming down from cruise altitude, the lush green landscape became visible through breaks in the clouds.  We were going to land in Russia.

While the purpose of the trip was business, I was determined to soak in as much of the experience as possible. I had a total of one paltry year of Russian language in college so I could at least sound out the words and recall a tiny bit of vocabulary. 

In the late 1990’s doing business in Russia- that is, buying Russian goods- could be complicated. This was late in Yeltsin’s term and a kind of cynical take on the free market was beginning to set in.  Earlier, the eastern bloc had imploded and the communist hold on Russia was in deconstruction. Under Yeltsin a select few had managed to amass wealth- the so-called Oligarchs.  But as a few like Khodorkovsky were to eventually learn, wealth does not automatically confer political power in Russia.

Doing business in Russia was a highly manual activity. In 2000, the start of the Putin years, Russia lacked much of the business infrastructure that we in the west take for granted. When I say “business infrastructure”, I refer to the whole picture- commercial credit; internationally compatible contract and tort law; credible mechanisms for the flow of currency; GAAP; a multimodal transportation network; a comprehensible market exchange for commodities; and a market place with suppliers and specialists for the many instruments of finance and insurance. 

In the Yeltsin years, many formerly state-owned factories came under control of people who conducted business in facilities through quiet arrangements behind the curtain.  Factories would operate at low intensity or would even be shut down until orders came in.  Workers were furlowed and operated taxi’s or did other odd jobs until an order arrived.  Maybe this still happens today.  I don’t know.

We needed product that was made by a very few specialists in the world and one of those vendors was in central Russia.  Russian manufacturers are as skilled as we are of course, but there are differences in business culture that may be hard to anticipate.  Western standards concerning documentation was a particular problem.  I recall that our vendor was quite carefree about lot traceability and packaging.   They also had the maddening habit of reusing old lot numbers.

Then there was the problem of shipping.  Russia did not then, and still may not, have anything remotely similar to Aldrich.  Now, you probably think of Aldrich as the “chemical supply house” and you’d be right. But I’m thinking of Aldrich as the “master of logistics”.  Logistics in Russia was a problem.  Ground transportation was unreliable. Our solution was to hire a local to bird-dog the whole process.  It was worth every penny.

One of the differences I found was in the attitude of the few manufacturers I was in contact with.  They were usually aware of western prices for their goods and were never afraid to demand Aldrich-type pricing.   In the west, the customer is king.  That is just taken for granted.  Uppity suppliers are soon former suppliers. 

What I ran into in Russia was something that I hadn’t seen anywhere else, including China or Taiwan.  Our Russian supplier wanted to dictate terms and was unwilling to budge- I think they call it “Vlast”.  We absolutely needed better prices for the raw material.  I’m sure that there were urgent arrangements behind the curtains that were part of the need to stand fast. But in the end, it was their absolute inflexibility that caused them to lose the business. 

While in Russia I did try to source other raw materials and “vendors” who could supply spot buys of particular compounds.  At the time, many chemical factories were partially shuttered, so custom chemical processing capacity was very much hit and miss.  Processing equipment sat in dark and idled buildings waiting for a purchase order and prepayment. 

We met with principals in an empty flat to talk about the manufacture of custom compounds. But the same problem always arose. They wanted cash up front, preferably deposited in a European bank.  I was very clear that this was not the transaction model that we were accustomed to and in fact, this requirement was a showstopper. My Russian contacts were mystified that an American would come all this way only to refuse to pony up the cash to get the ball rolling. And that is where my attempts at trying to do business with Russia ended. 

The operators of the factories I was in contact with had the pots and pans, skilled staff, and expertise in the technology- these guys were first rate technocrats. At first glance, what they lacked was the benefit of investment capital to plow into their operations to find and service customers.  But, digging deeper, it wan’t just the hard cash they lacked. There was a system-wide lack of free market history and culture that, elsewhere, would have provided the institutions and mechanisms to exploit opportunity. 

I admire Russia and I believe that they will eventually get their system working well.  But they do need to get away from the fascination with the strongman model of governance. From my travels I have concluded that countries with cultures that date far back are simultaneously blessed and cursed by it.  They are blessed by the warm embrace of cultural richness. But they are also cursed by it because it can be a sort of ball and chain that complicates the adoption of change.

Note: This was written a few months prior to posting.

Copyright 2007