There is a new kind of buzz in the anesthesia community these days. News of a “selective” muscle relaxant binding agent hit the web in a big way. Even Forbes made notice. Sugammadex, a proprietary cyclodextrin available from Organon, has the ability to bring post-operative patients out from under the influence of muscle relaxant drugs rapidly and safely. It does this by host-guest coordination of drug molecules in the blood stream, effectively lowering the blood titer of active drug. The cyclodextrin acts as a kind of sheath or molecular condom to prevent binding of the certain active relaxant drugs to the receptors. The results are apparently startling to the numbing and gas passing community.
Lamentations on Chemistry
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Lamentations on Chemistry 
Finally! We’ve heard of this agent for 2 years, and the advisory committee has unanimously recommended approval. This will be revolutionary for muscle relaxation reversal. Does Organon have any prediction when it will be available?
Good question. I really don’t know. Their website may provide a clue. It is a very clever product. My hat is off to whomever invented it.
SGP
Why do you think the FDA issued a “non-approval letter,” after its Advisory Committee’s unanimous recommendation for approval?
Hi John, I’ll have to see what it is that you refer to.
I have been trying to locate John L. Gueriguian, one of my customers, for whom I do not have an email address. My catalogues are only issued now by email and I would like to include him in my database. If I have actually reached Dr. Gueriguian or his office, please let him see this message (I know he is a busy man). Thank you. Carl Sandler Berkowitz, Out-of-Print Books for Scholars, 30 Gordon Road, Middletown, NY 10941-3345 berkowitz@frontiernet.net
Carl, any chance you could stop spamming! You have just emailed users on my message board touting for business. Plain and simple SPAM. Fuck off and don’t do it again.